AIs, Superflies, and the Path to Immortality
Interpretation of genetic data from fruit flies bred for longevity suggests the major culprit may not be accumulated damage…
Search Results for: michael rose
History
Genescient was founded in 2006 to genomically sequence the Methuselah flies. These flies were selectively bred for health and longevity over 27 years by Dr. Michael Rose. The objective of the sequencing experiment was to determine the genomic differences between the Methuselah flies and normal flies. The analysis revealed significant differences in the gene expression […]
Genetic Surprises
This Discover magazine article from 1992, discusses Methuselah genes.
Why Fruit Flies?
Many biomedical research efforts use mice or rats as animal models; at Genescient we focus on fruit flies (Drosophila), with a methodology of taking discoveries made using flies and then testing them on rodents and humans. One reason is that, due to their short lifespan, it is possible to evolve many generations of fruit flies […]
Adaptation, Aging, and Genomic Information
Aging is not simply an accumulation of damage or inappropriate higher-order signaling. Aging occurs because…
Evolution of ageing since Darwin
Evolutionary biology provides the only cogent, formally developed, and experimentally corroborated theory for biological ageing. In this essay, we supply a brisk run through the highlights of evolutionary research on the biology of ageing.
Live Longer With Evolution? Evidence May Lie in Fruit Flies
Through selective breeding, Dr. Rose was able to create a long-lived line of creatures he called Methuselah flies. He then put his research into reverse and developed flies with much shortened life spans.