Winter Quarter Our paper, “Multipath Natural Product Suplement Supresses Dementia Symptoms in Amyloid-B and Tau Transgenic Drosophila” is published in The Journal of Biology and Medical Research in January. Work continues on a paper detailing our human pilot study results, “Botanical Mixture Stabilizes Cognitive Function in Patients with Mild and Moderate Alzheimer’s Disease.” Spring Quarter […]
Winter Quarter Work continues on a paper that describes our transgenic Alzheimer’s fly model and the human pilot study we conducted as a result of studies using that model. Some preliminary data analysis of the MX100a patient registry, which has grown to over 150 individuals, shows that the human pilot results are in fact being […]
Winter Quarter Our Gen31 experiment assays the transgenic Tau Alzheimer’s Disease (AD) flies and our “B” flies with MX100a, memantine (Namenda), and combinations of the two therapies. Memantine (Namenda), is one of only a few “first line” therapies used to treat AD. Genescient made the decision to test memantine using our fly model to validate […]
Genescient’s Methuselah flies are more vigorous. “They beat up the other flies and take their women away,” said Gregory Benford, a retired UC Irvine physics professor.
Winter Quarter Dr. Robin Mockett, at University of Alabama, confirmed the longevity benefits of MX-100 on his fruit flies under certain conditions. We begin writing the MX-100 paper, reporting these longevity results, with the goal of submitting to Plos One. The Genescient Lab begins planning transgenic fly experiments with the 9 genes that we think […]
Winter Quarter We collected the remaining O flies (“RO”) from the Rose lab at UCI, and Genescient now houses ALL O flies. In our Gen9 experiment, we tested MX-100 again. This time, we included a cohort of flies that didn’t get the treatment until mid-life. The reasoning behind this was to simulate what it might […]
Winter Quarter First DNA extraction of O and B flies using a QPCR kit. Samples were sent to Illumina for sequencing. Started testing a resveratrol analog, Pine Bark extract, on “B” flies at the recommendation of Dr. Spindler at UCR. We tested varying doses of Pine Bark extract alone and in combination with Uridine, which […]
Interpretation of genetic data from fruit flies bred for longevity suggests the major culprit may not be accumulated damage…
Genescient study suggests that, when long-term effects are considered, two commonly ingested stimulants are not created equal. The study compares…
Aging is not simply an accumulation of damage or inappropriate higher-order signaling. Aging occurs because…